Version 2.77

Part Description

LP115359-4   Chlamydia trachomatis & Neisseria gonorrhoeae
Target amplification assays are based on the ability of complementary oligonucleotide primers to specifically anneal and allow enzymatic amplification of the target nucleic acid strands. The GEN-PROBE APTIMA Combo 2 Assay replicates a specific region of the 23S rRNA from CT and a specific region of the 16S rRNA from GC via DNA intermediates. A unique set of primers is used for each target molecule. Detection of the rRNA amplification product sequences (amplicon) is achieved using nucleic acid hybridization. Single-stranded chemiluminescent DNA probes, which are complementary to a region of each target amplicon, are labeled with different acridinium ester molecules. The labeled DNA probes combine with amplicon to form stable RNA:DNA hybrids. The Selection Reagent differentiates hybridized from unhybridized probe, eliminating the generation of signal from unhybridized probe. During the detection step, light emitted from the labeled RNA:DNA hybrids is measured as photon signals in a luminometer, and are reported as Relative Light Units (RLU). In DKA, differences in the kinetic profiles of the CT and GC labeled probes allow for the differentiation of signal; kinetic profiles are derived from measurements of photon output during the detection read time. The chemiluminescent detection reaction for CT signal has very rapid kinetics and has the "flasher" kinetic type. The chemiluminescent detection reaction for GC signal is relatively slower and has the "glower" kinetic type. Assay results are determined by a cut-off based on the total RLU and the kinetic curve type. Source: Regenstrief Help

Fully-Specified Name

Component
Chlamydia trachomatis & Neisseria gonorrhoeae DNA
Property
Prid
Time
Pt
System
XXX
Scale
Nom
Method
Probe.amp.sig

Additional Names

Short Name
C trach+GC DNA Spec Probe+sig amp
Display Name
C. trachomatis and N. gonorrhoeae DNA Probe+sig amp Nom (Specimen)
Consumer Name Alpha Get Info
Chlamydia trachomatis & Neisseria gonorrhoeae, Specimen

Example Answer List: LL1501-7

Source: Association of Public Health Laboratories
Answer Code Score Answer ID
Chlamydia trachomatis detected LA16153-1
Chlamydia trachomatis not detected LA16154-9
Chlamydia trachomatis inconclusive LA16155-6
Chlamydia trachomatis equivocal LA16157-2
Neisseria gonorrhoeae detected LA16150-7
Neisseria gonorrhoeae not detected LA16151-5
Neisseria gonorrhoeae inconclusive LA16152-3
Neisseria gonorrhoeae equivocal LA16156-4

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.69
Change Reason
Changed + to & in Component because this is a Prid/Nom term that is used for assays that can detect and differentiate between the organisms.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
90766-7 HEDIS 2019 Value Sets
94137-7 HEDIS 2020 Value Sets
96068-2 HEDIS MY 2020 Value Sets

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Chlamydia trachomatis & Neisseria gonorrhoeae DNA:Nachweis oder Identität:Zeitpunkt:XXX:Nominal:Sondendetektion mit Signalamplifikation
es-ES Spanish (Spain) Chlamydia trachomatis & Neisseria gonorrhoeae ADN:Presencia o identidad:Punto temporal:XXX:Nom:Sonda con amplificación de señal
es-MX Spanish (Mexico) ADN de Chlamydia trachomatis y Neisseria gonorrhoeae:Presencia o identidad:Punto temporal:XXX:Nominal:Sonda con amplificación de señal
fr-CA French (Canada) Chlamydia trachomatis & Neisseria gonorrhoeae , ADN:Présence ou identité:Temps ponctuel:XXX:Nominal:Sonde avec amplification du signal
fr-FR French (France) Chlamydia trachomatis et Neisseria gonorrhoeae ADN:Identification:Ponctuel:Milieux divers:Résultat nominal:PCR amplification du signal
it-IT Italian (Italy) Chlamydia trachomatis & Neisseria gonorrhoeae DNA:Prid:Pt:XXX:Nom:Sonda.amp.sig
Synonyms: Chlamydia trachomatis e Neisseria gonorrhoeae Microbiologia Presenza o Identità Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del segnale Sonda di DNA
nl-NL Dutch (Netherlands) Chlamydia trachomatis & Neisseria gonorrhoeae DNA:identificator:moment:XXX:nominaal:probe.amp.sig
pt-BR Portuguese (Brazil) Chlamydia trachomatis+Neisseria gonorrhoeae DNA:Ident:Pt:XXX:Nom:Sonda com amplificação de sinal
Synonyms: ; N gonorrhoea; N gonorrhoeae; Gono; GC; Gonorrhea; Deoxyribonucleic acid; C trach+GC; CT/GC; C trac; C trachomatis; Chlam trac; C trach; C tracho; CT; Trachoma; Lymphogranuloma venereum; LGV; Identity or presence; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Nominal; bDNA; HPA; Hybidization Protection Assay; Bdn-A; Branched Chain DNA; Hybrid Capture; Probe with signal amplification; Hybrid Capture nucleic acid hybridization; HC; Amp Prb; Probe with ampification; DNA probe; Amplification; Amplified; Chlamid; Microbiology
ru-RU Russian (Russian Federation) Chlamydia trachomatis & Neisseria gonorrhoeae ДНК:ПрИд:ТчкВрм:XXX:Ном:Проба.усил.сигн
Synonyms: ДНК проба;ДНК зонд Номинальный;Именной Присутствие или Идентификация Проба с сигнала усилением Точка во времени;Момент
zh-CN Chinese (China) 沙眼衣原体与淋病奈瑟菌 DNA:存在与否或特征标识:时间点:XXX:名义型:探针法.基因扩增.信号
Synonyms: 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 借助信号扩增的探针方法;借助信号扩增的探针法;探针法.扩增.信号;支链 DNA;支链 DNA（Branched Chain DNA，bDNA）;杂交保护分析;杂交保护分析（Hybidization Protection Assay，HPA）;杂交保护测定;杂种捕获;杂种捕获（Hybrid Capture）;杂种捕获核酸杂交（Hybrid Capture nucleic acid hybridization） 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 去氧核糖核酸;脱氧核糖核酸 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 存在;存在与否;特征标识;身份;身份标识 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 椒疮;沙眼;砂眼;粒性结膜炎;颗粒性结膜炎 沙眼衣原体+淋病奈瑟菌（淋球菌、淋病、淋病双球菌、淋病奈瑟氏菌）;C trach+GC;CT/GC 沙眼衣原体与淋病奈瑟菌（淋球菌、淋病、淋病双球菌、淋病奈瑟氏菌） 淋球菌 DNA 淋球菌;淋病;淋病双球菌;淋病奈瑟氏菌 淋病奈瑟氏菌 DNA 经过扩增的 脱氧核糖核酸探针 衣原体属

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=43405-0